发明申请
US20140331345A1 SEQUENCE OF PORCINE ROSA26 LOCUS AND METHODS OF USING THE SAME
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PORCINE ROSA26位置的序列及其使用方法
- 专利标题： SEQUENCE OF PORCINE ROSA26 LOCUS AND METHODS OF USING THE SAME
- 专利标题（中）： PORCINE ROSA26位置的序列及其使用方法
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申请号： US13887316申请日： 2013-05-04
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公开(公告)号： US20140331345A1公开(公告)日： 2014-11-06
- 发明人: Qingran Kong , Meiling Wu , Zhonghua Liu
- 申请人： Qingran Kong , Meiling Wu , Zhonghua Liu
- 优先权： CN201210134764.0 20130504
- 主分类号： C12N15/90
- IPC分类号： C12N15/90
摘要：
The present invention provides a 5 kb sequence of porcine ROSA26 locus, which can be used for site-specific integration of an exogenous gene into a pig genome. The present invention also provides a gene targeting vector with a 3′ and 5′ arm of the porcine ROSA26 sequence, wherein a target gene can be inserted between the 3′ and 5′ arm sequence. The gene targeting vector can be used to generate transgenic pigs with stable and ubiquitous expression of the target gene.
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