公开(公告)号：US20140331345A1

公开(公告)日：2014-11-06

申请号：US13887316

申请日：2013-05-04

申请人： Qingran Kong ,  Meiling Wu ,  Zhonghua Liu

发明人： Qingran Kong ,  Meiling Wu ,  Zhonghua Liu

IPC分类号： C12N15/90

CPC分类号： C12N15/907 ,  A01K67/0275 ,  A01K2217/07 ,  A01K2227/108 ,  C07H21/04 ,  C12N15/79 ,  C12N15/85 ,  C12N15/8509

摘要： The present invention provides a 5 kb sequence of porcine ROSA26 locus, which can be used for site-specific integration of an exogenous gene into a pig genome. The present invention also provides a gene targeting vector with a 3′ and 5′ arm of the porcine ROSA26 sequence, wherein a target gene can be inserted between the 3′ and 5′ arm sequence. The gene targeting vector can be used to generate transgenic pigs with stable and ubiquitous expression of the target gene.

摘要翻译： 本发明提供了一种5kb的猪ROSA26基因座序列，其可用于将外源基因的位点特异性整合到猪基因组中。 本发明还提供了具有猪ROSA26序列的3'和5'臂的基因靶向载体，其中靶基因可插入3'和5'臂序列之间。 基因靶向载体可用于产生具有靶基因的稳定且普遍存在的转基因猪。

公开(公告)号：US09090913B2

公开(公告)日：2015-07-28

申请号：US13887316

申请日：2013-05-04

申请人： Qingran Kong ,  Meiling Wu ,  Zhonghua Liu

发明人： Qingran Kong ,  Meiling Wu ,  Zhonghua Liu

IPC分类号： C12N15/00 ,  C07H21/04 ,  C12N15/90 ,  C12N15/79 ,  C12N15/85

CPC分类号： C12N15/907 ,  A01K67/0275 ,  A01K2217/07 ,  A01K2227/108 ,  C07H21/04 ,  C12N15/79 ,  C12N15/85 ,  C12N15/8509

摘要： The present invention provides a 5 kb sequence of porcine ROSA26 locus, which can be used for site-specific integration of an exogenous gene into a pig genome. The present invention also provides a gene targeting vector with a 3′ and 5′ arm of the porcine ROSA26 sequence, wherein a target gene can be inserted between the 3′ and 5′ arm sequence. The gene targeting vector can be used to generate transgenic pigs with stable and ubiquitous expression of the target gene.

摘要翻译： 本发明提供了一种5kb的猪ROSA26基因座序列，其可用于将外源基因的位点特异性整合到猪基因组中。 本发明还提供了具有猪ROSA26序列的3'和5'臂的基因靶向载体，其中靶基因可插入3'和5'臂序列之间。 基因靶向载体可用于产生具有靶基因的稳定且普遍存在的转基因猪。

公开(公告)号：US08207122B2

公开(公告)日：2012-06-26

申请号：US12697320

申请日：2010-02-01

申请人： Songping Liang ,  Zhonghua Liu

发明人： Songping Liang ,  Zhonghua Liu

IPC分类号： A61P35/00 ,  C07K14/435

CPC分类号： C07K14/43518 ,  A61K38/00

摘要： An anti-cancer bioactive peptide having an amino acid sequence as shown in SEQ ID NO.1, or a functional analogue thereof prepared by substitution, insertion, or deletion of one or more amino acids of SEQ ID NO. 1, or a peptide having 90% homology in amino acid sequence with that of SEQ ID NO. 1. The anti-cancer bioactive peptide of the invention can selectively kill cancer cells and exhibit low cytotoxicity against normal cells.

摘要翻译： 具有如SEQ ID NO.1所示的氨基酸序列的抗癌生物活性肽或其功能类似物，其通过SEQ ID NO.1的一个或多个氨基酸的取代，插入或缺失而制备。 1，或者氨基酸序列具有与SEQ ID NO：1的氨基酸序列具有90％同源性的肽。 本发明的抗癌生物活性肽可以选择性杀死癌细胞，对正常细胞表现出低细胞毒性。

公开(公告)号：US20090129433A1

公开(公告)日：2009-05-21

申请号：US12269321

申请日：2008-11-12

申请人： Bo ZHANG ,  Pengfei Zuo ,  Xianliang He ,  Zhonghua Liu

发明人： Bo ZHANG ,  Pengfei Zuo ,  Xianliang He ,  Zhonghua Liu

IPC分类号： G01K3/00

CPC分类号： G01K7/42 ,  G01K13/002

摘要： A method and a device for temperature prediction or measurement are disclosed. The method comprises: acquiring temperature data outputted from a thermometer probe; selecting some temperature data within a valid time period from the acquired data; determining a first specific time point according to the slope change rate of the temperature curve within the valid time period and an initial temperature within the valid time period; determining a second specific time point according to the slope at or before the first specific time point; calculating a value of temperature y according to an hyperbolic formula; determining a final temperature of the object according to the maximum slope of the temperature curve in the valid time period, the initial temperature of the temperature curve in the valid time period, and the value of temperature y.

摘要翻译： 公开了一种用于温度预测或测量的方法和装置。 该方法包括：获取从温度计探针输出的温度数据; 在获取的数据的有效时间段内选择一些温度数据; 根据有效时间段内的温度曲线的斜率变化率和有效时间段内的初始温度来确定第一特定时间点; 根据第一特定时间点之前或之前的斜率确定第二特定时间点; 根据双曲线公式计算温度y的值; 根据有效时间段内的温度曲线的最大斜率，有效时间段内的温度曲线的初始温度和温度y的值，确定物体的最终温度。

公开(公告)号：US20110063256A1

公开(公告)日：2011-03-17

申请号：US12921696

申请日：2009-04-29

申请人： Xinlin Ye ,  Jianjun Liu ,  Zhonghua Liu ,  Xinbin Liu

发明人： Xinlin Ye ,  Jianjun Liu ,  Zhonghua Liu ,  Xinbin Liu

IPC分类号： G06F3/042 ,  H04N5/225

CPC分类号： G06F3/0428

摘要： An image sensor for a touch screen, which is installed at an edge of the touch screen and comprises an image sensing element and an optical imaging system, wherein the optical imaging system comprises: at least two separated lenses to constitute at least two optical paths, wherein each of the lenses includes a concavo-convex lens, an objective lens of each of the lenses is faced to the touch screen, an overlapping area of fields of the view of the objective lenses covers the touch screen, a touch object on the touch screen is imaged by each of the optical paths in the optical imaging system respectively, and the formed image is projected on the image sensing element. The image sensor can locate the touch object by utilizing stereo photography. Moreover, the optical imaging system can utilize the interlocked electronic shutters to realize time division multiplex of the image sensing element by the different optical paths, or utilize individual optical paths to realize area division multiplex of the image sensing element.

摘要翻译： 一种用于触摸屏的图像传感器，其安装在触摸屏的边缘并且包括图像感测元件和光学成像系统，其中所述光学成像系统包括：至少两个分离的透镜，以构成至少两个光学路径， 其中每个透镜包括凹凸透镜，每个透镜的物镜面向触摸屏，物镜的视场的重叠区域覆盖触摸屏，触摸上的触摸对象 屏幕分别通过光学成像系统中的每个光路成像，并且将形成的图像投影到图像感测元件上。 图像传感器可以通过立体摄影来定位触摸物体。 此外，光学成像系统可以利用互锁的电子快门来实现不同光路的图像感测元件的时分复用，或者利用各个光路实现图像感测元件的区域分割多路复用。

公开(公告)号：US08197128B2

公开(公告)日：2012-06-12

申请号：US12269321

申请日：2008-11-12

申请人： Bo Zhang ,  Pengfei Zuo ,  Xianliang He ,  Zhonghua Liu

发明人： Bo Zhang ,  Pengfei Zuo ,  Xianliang He ,  Zhonghua Liu

IPC分类号： G01K3/00 ,  G01K3/08 ,  G01K5/22 ,  A61B5/01

CPC分类号： G01K7/42 ,  G01K13/002

摘要： A method and a device for temperature prediction or measurement are disclosed. The method comprises: acquiring temperature data outputted from a thermometer probe; selecting some temperature data within a valid time period from the acquired data; determining a first specific time point according to the slope change rate of the temperature curve within the valid time period and an initial temperature within the valid time period; determining a second specific time point according to the slope at or before the first specific time point; calculating a value of temperature y according to an hyperbolic formula; determining a final temperature of the object according to the maximum slope of the temperature curve in the valid time period, the initial temperature of the temperature curve in the valid time period, and the value of temperature y.

摘要翻译： 公开了一种用于温度预测或测量的方法和装置。 该方法包括：获取从温度计探针输出的温度数据; 在获取的数据的有效时间段内选择一些温度数据; 根据有效时间段内的温度曲线的斜率变化率和有效时间段内的初始温度来确定第一特定时间点; 根据第一特定时间点之前或之前的斜率确定第二特定时间点; 根据双曲线公式计算温度y的值; 根据有效时间段内的温度曲线的最大斜率，有效时间段内的温度曲线的初始温度和温度y的值，确定物体的最终温度。

公开(公告)号：US09983736B1

公开(公告)日：2018-05-29

申请号：US15437064

申请日：2017-02-20

申请人： Peigen Jiang ,  Zhonghua Liu

发明人： Peigen Jiang ,  Zhonghua Liu

IPC分类号： G06F3/042

CPC分类号： G06F3/0421

摘要： An optical touch sensor is disclosed which includes a first and a second light detector mounted side by side forming a gap therebetween, the first and the second light detector commonly facing a touch sensing surface area, and a light emitter mounted behind the first and second light detector and aligned with the gap, wherein a light beam emitted from the light emitter can pass through the gap.

公开(公告)号：US08451252B2

公开(公告)日：2013-05-28

申请号：US12921696

申请日：2009-04-29

申请人： Xinlin Ye ,  Jianjun Liu ,  Zhonghua Liu ,  Xinbin Liu

发明人： Xinlin Ye ,  Jianjun Liu ,  Zhonghua Liu ,  Xinbin Liu

IPC分类号： G06F3/042

CPC分类号： G06F3/0428

摘要： An image sensor for a touch screen, which is installed at an edge of the touch screen and comprises an image sensing element and an optical imaging system, wherein the optical imaging system comprises: at least two separated lenses to constitute at least two optical paths, wherein each of the lenses includes a concavo-convex lens, an objective lens of each of the lenses is faced to the touch screen, an overlapping area of fields of the view of the objective lenses covers the touch screen, a touch object on the touch screen is imaged by each of the optical paths in the optical imaging system respectively, and the formed image is projected on the image sensing element. The image sensor can locate the touch object by utilizing stereo photography. Moreover, the optical imaging system can utilize the interlocked electronic shutters to realize time division multiplex of the image sensing element by the different optical paths, or utilize individual optical paths to realize area division multiplex of the image sensing element.

摘要翻译： 一种用于触摸屏的图像传感器，其安装在触摸屏的边缘并且包括图像感测元件和光学成像系统，其中所述光学成像系统包括：至少两个分离的透镜，以构成至少两个光学路径， 其中每个透镜包括凹凸透镜，每个透镜的物镜面向触摸屏，物镜的视场的重叠区域覆盖触摸屏，触摸上的触摸对象 屏幕分别通过光学成像系统中的每个光路成像，并且将形成的图像投影到图像感测元件上。 图像传感器可以通过立体摄影来定位触摸物体。 此外，光学成像系统可以利用互锁的电子快门来实现不同光路的图像感测元件的时分复用，或者利用各个光路实现图像感测元件的区域分割多路复用。