发明申请
- 专利标题： 1,4,5,6-TETRAHYDRO-PYRIMIDIN-2-YLAMINE COMPOUNDS
- 专利标题（中）： 1,4,5,6-四氢吡啶-2-基胺化合物
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申请号： US14326861申请日： 2014-07-09
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公开(公告)号： US20140336208A1公开(公告)日： 2014-11-13
- 发明人: David Banner , Emanuele Gabellieri , Wolfgang Guba , Hans Hilpert , Benoit Hornsperger , Roland Humm , Harald Mauser , Alexander V. Mayweg , Robert Narquizian , Emmanuel Pinard , Mark Rogers-Evans , Thomas Woltering , Wolfgang Wostl
- 申请人： Hoffmann-La Roche Inc.
- 优先权： EP10172299.9 20100809
- 主分类号： C07D417/12
- IPC分类号： C07D417/12 ; C07D239/70 ; C07D405/12 ; C07D401/12 ; C07D413/12 ; C07D409/12 ; C07D239/22 ; C07D403/12
摘要：
This invention relates to compounds of the formula wherein R1 to R9 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE2 inhibitors and can be used as medicaments for the therapeutic and/or prophylactic treatment of diseases such as diabetes, particularly type 2 diabetes, and other metabolic disorders.
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