发明申请
US20140342006A1 Methods for Preparing Injectable Protein Microparticle Suspensions
审中-公开
准备注射蛋白微粒悬浮液的方法
- 专利标题: Methods for Preparing Injectable Protein Microparticle Suspensions
- 专利标题(中): 准备注射蛋白微粒悬浮液的方法
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申请号: US14209350申请日: 2014-03-13
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公开(公告)号: US20140342006A1公开(公告)日: 2014-11-20
- 发明人: Tiejun Li
- 申请人: Ansun Biopharma, Inc.
- 申请人地址: US CA San Diego
- 专利权人: Ansun Biopharma, Inc.
- 当前专利权人: Ansun Biopharma, Inc.
- 当前专利权人地址: US CA San Diego
- 主分类号: A61K9/16
- IPC分类号: A61K9/16 ; A61K38/47
摘要:
A method for preparing a microparticle suspension, which comprises: (a) providing protein microparticles having a median diameter between 5 and 13 microns and a GSD less than 2.5; (b) combining the microparticles with a liquid, pharmaceutically acceptable, water miscible media to create a first mixture; (c) adding an aqueous media to the first mixture to create second mixture; and (d) mixing the second mixture to create a microparticle suspension is described. The suspension are injectable even when they contain a relatively high concentration of protein.
公开/授权文献
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