发明申请
US20140342006A1 Methods for Preparing Injectable Protein Microparticle Suspensions 审中-公开
准备注射蛋白微粒悬浮液的方法

  • 专利标题: Methods for Preparing Injectable Protein Microparticle Suspensions
  • 专利标题(中): 准备注射蛋白微粒悬浮液的方法
  • 申请号: US14209350
    申请日: 2014-03-13
  • 公开(公告)号: US20140342006A1
    公开(公告)日: 2014-11-20
  • 发明人: Tiejun Li
  • 申请人: Ansun Biopharma, Inc.
  • 申请人地址: US CA San Diego
  • 专利权人: Ansun Biopharma, Inc.
  • 当前专利权人: Ansun Biopharma, Inc.
  • 当前专利权人地址: US CA San Diego
  • 主分类号: A61K9/16
  • IPC分类号: A61K9/16 A61K38/47
Methods for Preparing Injectable Protein Microparticle Suspensions
摘要:
A method for preparing a microparticle suspension, which comprises: (a) providing protein microparticles having a median diameter between 5 and 13 microns and a GSD less than 2.5; (b) combining the microparticles with a liquid, pharmaceutically acceptable, water miscible media to create a first mixture; (c) adding an aqueous media to the first mixture to create second mixture; and (d) mixing the second mixture to create a microparticle suspension is described. The suspension are injectable even when they contain a relatively high concentration of protein.
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