发明申请
US20140343047A1 TETRANDRINE DERIVATIVES WITH SUBSTITUTED 5-CARBON, PREPARATION METHOD AND USE THEREOF
有权
具有取代的5碳的四氢呋喃衍生物，其制备方法和用途
- 专利标题： TETRANDRINE DERIVATIVES WITH SUBSTITUTED 5-CARBON, PREPARATION METHOD AND USE THEREOF
- 专利标题（中）： 具有取代的5碳的四氢呋喃衍生物，其制备方法和用途
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申请号： US14239759申请日： 2012-08-20
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公开(公告)号： US20140343047A1公开(公告)日： 2014-11-20
- 发明人: Rongzhen Xu , Frank Rong , Fuwen Xie , Hongxi Lai
- 申请人： Rongzhen Xu , Frank Rong , Fuwen Xie , Hongxi Lai
- 申请人地址： CN Zhejiang
- 专利权人： HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD.
- 当前专利权人： HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： CN Zhejiang
- 优先权： CNPCT/CN2011/078622 20110819
- 国际申请： PCT/CN2012/080384 WO 20120820
- 主分类号： C07D491/22
- IPC分类号： C07D491/22
摘要：
The present invention belongs to the field of natural medicine and pharmaceutical chemistry and specifically relates to novel 5-substituted tetrandrine derivatives of formula (I) and a pharmaceutically acceptable adduct, complex and salt thereof, to a process for the preparation of these compounds, pharmaceutical compositions containing such compounds and their use in preparing antineoplastic medicaments.
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