- 专利标题： BETA-ALANINE/ALPHA-KETOGLUTARATE AMINOTRANSFERASE FOR 3-HYDROXYPROPIONIC ACID PRODUCTION
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申请号： US13230217申请日： 2011-09-12
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公开(公告)号： US20140349376A1公开(公告)日： 2014-11-27
- 发明人: Holly Jean Jessen , Hans H. Liao , Steven John Gort , Olga V. Selifonova
- 申请人： Holly Jean Jessen , Hans H. Liao , Steven John Gort , Olga V. Selifonova
- 专利权人： Cargill, Incorporated
- 当前专利权人： Cargill, Incorporated
- 主分类号： C12N9/10
- IPC分类号： C12N9/10
摘要：
The present disclosure provides novel beta-alanine/alpha ketoglutarate aminotransferase nucleic acid and protein sequences having increased biological activity. Also provided are cells containing such enzymes, as well as methods of their use, for example to produce malonyl semialdehyde and downstream products thereof, such as 3-hydroxypropionic acid and derivatives thereof.
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