Invention Application
- Patent Title: Preparation of 3,5-Dioxo Hexanoate Ester in Two Steps
- Patent Title (中): 两步制备3,5-二氧代己酸酯
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Application No.: US14471682Application Date: 2014-08-28
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Publication No.: US20140371451A1Publication Date: 2014-12-18
- Inventor: Christian Noti , Guixian Hu , Barry Jackson
- Applicant: Lonza Ltd
- Priority: EP11002723.2 20110401; EP11002922.0 20110407; EP11006862.4 20110823; EP11006872.3 20110823; EP11007605.6 20110919; EP11007606.4 20110919; EP12150867.5 20120112; EP12150868.3 20120112
- Main IPC: C07D319/06
- IPC: C07D319/06 ; C07D207/34 ; C07C67/297 ; C07D239/42
Abstract:
The invention discloses a method for the preparation of tert-butyl 6-chloro-3,5-dioxohexanoate from Meldrum's acid derivative and its use for the preparation of tert-butyl (4R,6S)-(6-hydroxymethyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate (BHA), Rosuvastatin and Atorvastatin.
Public/Granted literature
- US09296718B2 Preparation of 3,5-dioxo hexanoate ester in two steps Public/Granted day:2016-03-29
Information query
