发明申请
US20140377361A1 STABLE METAL ION-LIPID POWDERED PHARMACEUTICAL COMPOSITIONS FOR DRUG DELIVERY
审中-公开
稳定的金属离子粉末药物组合物用于药物递送
- 专利标题: STABLE METAL ION-LIPID POWDERED PHARMACEUTICAL COMPOSITIONS FOR DRUG DELIVERY
- 专利标题(中): 稳定的金属离子粉末药物组合物用于药物递送
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申请号: US14478573申请日: 2014-09-05
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公开(公告)号: US20140377361A1公开(公告)日: 2014-12-25
- 发明人: Luis A. DELLAMARY , Jean RIESS , Ernest G. SCHUTT , Jeffry G. WEERS , Thomas E. TARARA
- 申请人: Luis A. DELLAMARY , Jean RIESS , Ernest G. SCHUTT , Jeffry G. WEERS , Thomas E. TARARA
- 申请人地址: CH Basel
- 专利权人: NOVARTIS AG
- 当前专利权人: NOVARTIS AG
- 当前专利权人地址: CH Basel
- 主分类号: A61K9/16
- IPC分类号: A61K9/16 ; A61K31/7036 ; A61K31/496 ; A61K9/14
摘要:
A microparticle for drug delivery comprises an active agent and an excipient, the excipient comprising a metal ion-lipid complex. The metal ion is chosen from the group consisting of lanthanide metals, actinide metals, group IIa and IIIb metals, transition metals or mixtures thereof. The lipid comprises a phospholipid. The complex results in a glass transition temperature increase of the microparticle.
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