发明申请
US20140378498A1 Tamper Resistant Composition Comprising Hydrocodone And Acetaminophen For Rapid Onset And Extended Duration Of Analgesia
有权
包含氢可酮和对乙酰氨基酚的抗鞣剂组合物用于快速起始和延长的止痛持续时间
- 专利标题： Tamper Resistant Composition Comprising Hydrocodone And Acetaminophen For Rapid Onset And Extended Duration Of Analgesia
- 专利标题（中）： 包含氢可酮和对乙酰氨基酚的抗鞣剂组合物用于快速起始和延长的止痛持续时间
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申请号： US14479129申请日： 2014-09-05
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公开(公告)号： US20140378498A1公开(公告)日： 2014-12-25
- 发明人: KRISHNA DEVARAKONDA , MICHAEL J. GIULIANI , VISHAL K. GUPTA , RALPH A. HEASLEY , SUSAN SHELBY
- 申请人： MALLINCKRODT LLC
- 主分类号： A61K47/10
- IPC分类号： A61K47/10 ; A61K31/167 ; A61K31/485
摘要：
The present disclosure provides an extended release pharmaceutical composition comprising hydrocodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-induced hepatic damage in a subject being treated with an acetaminophen containing composition, as well as methods for treating pain in a subject in need thereof.
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