There is provided a new apparatus, system, and method of use for laser speckle imaging that allows for omni-directional viewing. The omni-directional viewing can include a reflector and switches configured for switching the illumination on the lumenal tissue such that the light reflected from the lumenal tissue at any given time is reflected from one or more substantially non-overlapping sections of a lumenal tissue. This apparatus may be particularly useful for tissue analysis such as analysis of vulnerable plaque.