发明申请
US20150056655A1 EXPRESSION CONSTRUCTS AND METHODS FOR EXPRESSING POLYPEPTIDES IN EUKARYOTIC CELLS
审中-公开
用于表达欧洲核细胞中多肽的表达结构和方法
- 专利标题： EXPRESSION CONSTRUCTS AND METHODS FOR EXPRESSING POLYPEPTIDES IN EUKARYOTIC CELLS
- 专利标题（中）： 用于表达欧洲核细胞中多肽的表达结构和方法
-
申请号： US14453328申请日： 2014-08-06
-
公开(公告)号： US20150056655A1公开(公告)日： 2015-02-26
- 发明人: Christel AEBISCHER-GUMY , Martin Bertschinger , Pierre Moretti
- 申请人： Glenmark Pharmaceuticals S.A.
- 优先权： EP13179375.4 20130806
- 主分类号： C07K16/46
- IPC分类号： C07K16/46 ; C12N15/85
摘要：
The invention relates to an expression construct for the expression of polypeptides in host cells using alternative splicing. The expression construct can be used for the expression of polypeptides such as antibodies, antibody fragments and bispecific antibodies by expressing the gene products required for protein expression at the ratio leading to the highest titres or the best product quality profile.
信息查询
