Invention Application
- Patent Title: KINETIC RESOLUTION
- Patent Title (中): 动力学分析
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Application No.: US14496157Application Date: 2014-09-25
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Publication No.: US20150073170A1Publication Date: 2015-03-12
- Inventor: Stephen Joseph CONNON , Aldo PESCHIULLI , Barbara PROCURANTI
- Applicant: THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF THE BOARD, OF THE COLLEGE OF THE
- Applicant Address: IE Dublin
- Assignee: THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF THE BOARD, OF THE COLLEGE OF THE
- Current Assignee: THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF THE BOARD, OF THE COLLEGE OF THE
- Current Assignee Address: IE Dublin
- Priority: EP09178565.9 20091209
- Main IPC: C07C327/22
- IPC: C07C327/22 ; C07C51/083
Abstract:
Whilst methodologies for the Kinetic Resolution of alcohols are well established, no analogous direct methods exist for the highly selective, direct catalytic Kinetic Resolution of thiols (i.e., R—SH). The present invention relates to a method for resolving stereoisomeric mixtures of thiols. In particular, the present invention relates to purely organocatalytic mediated resolution of enantiomeric mixtures of thiols without the need for enzymes. Also disclosed are some novel catalysts. Such catalysts may comprise a cinchona alkaloid-derived moiety.
Public/Granted literature
- US09346755B2 Kinetic resolution Public/Granted day:2016-05-24
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