Invention Application
- Patent Title: MICRO-RNAS INVOLVED IN MACULAR DEGENERATION
- Patent Title (中): MICRO-RNAS涉及到微量元素变性
-
Application No.: US14398330Application Date: 2013-05-02
-
Publication No.: US20150087693A1Publication Date: 2015-03-26
- Inventor: Shusheng Wang , Eric Olson , Qinbo Zhou
- Applicant: The Board of Regents of the University of Texas System , The Administrators of the Tulane Educational Fund
- Applicant Address: US LA New Orleans US TX Austin
- Assignee: The Administrators of the Tulane Educational Fund,The Board of Regents of the University of Texas System
- Current Assignee: The Administrators of the Tulane Educational Fund,The Board of Regents of the University of Texas System
- Current Assignee Address: US LA New Orleans US TX Austin
- International Application: PCT/US13/39197 WO 20130502
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K45/06 ; A61K31/713 ; A61K31/7105
Abstract:
The present invention relates to the involvement of miR function in the development of age-related macular degeneration (AMD). It is shown that miR-23, miR-24 and/or miR-27 are involved in pathologic neovascularization in AMD, and that agonism (miR-24) and inhibition (miR23/27) of the function of these molecules blocks events contributing to development and progression of disease.
Public/Granted literature
- US09598694B2 Micro-RNAs involved in macular degeneration Public/Granted day:2017-03-21
Information query
IPC分类:
