专利检索 ap:("The Board of Regents of the University of Texas System" OR "The Administrators of the Tulane Educational Fund") AND inv:"Qinbo Zhou" 第 1 页

1.

发明申请
MICRO-RNAS INVOLVED IN MACULAR DEGENERATION 有权
标题翻译： MICRO-RNAS涉及到微量元素变性

公开(公告)号：US20150087693A1

公开(公告)日：2015-03-26

申请号：US14398330

申请日：2013-05-02

申请人： The Board of Regents of the University of Texas System , The Administrators of the Tulane Educational Fund

发明人： Shusheng Wang , Eric Olson , Qinbo Zhou

IPC分类号： C12N15/113 , A61K45/06 , A61K31/713 , A61K31/7105

CPC分类号： C12N15/113 , A61K31/7105 , A61K31/713 , A61K45/06 , C12N2310/113 , C12N2310/14 , C12N2310/141 , C12N2310/3231

摘要： The present invention relates to the involvement of miR function in the development of age-related macular degeneration (AMD). It is shown that miR-23, miR-24 and/or miR-27 are involved in pathologic neovascularization in AMD, and that agonism (miR-24) and inhibition (miR23/27) of the function of these molecules blocks events contributing to development and progression of disease.

摘要翻译： 本发明涉及miR功能参与年龄相关性黄斑变性（AMD）的发展。显示miR-23，miR-24和/或miR-27参与AMD的病理性新生血管形成，并且这些分子的功能的激动（miR-24）和抑制（miR23 / 27）阻止事件有助于疾病的发展和进展。

2.

发明授权
Compositions and methods for treating vascular disorders 有权

公开(公告)号：US10400237B2

公开(公告)日：2019-09-03

申请号：US15448225

申请日：2017-03-02

申请人： The Administrators of the Tulane Educational Fund

发明人： Shusheng Wang , Qinbo Zhou

IPC分类号： A61K31/713 , C12N15/113 , A61K45/06 , C12N5/00

摘要： The present disclosure provides compositions and methods of their use to impair angiogenesis in a patient to treat indications including, but not limited to, tumor growth, age-related macular degeneration, and metastasis. Also provided are compositions and methods for promoting angiogenesis in patients in need thereof.

3.

发明授权
Micro-RNAs involved in macular degeneration 有权

公开(公告)号：US09598694B2

公开(公告)日：2017-03-21

申请号：US14398330

申请日：2013-05-02

申请人： The Board of Regents of the University of Texas System

发明人： Shusheng Wang , Eric Olson , Qinbo Zhou

IPC分类号： C12N15/113 , A61K31/7105 , A61K31/713 , A61K45/06

CPC分类号： C12N15/113 , A61K31/7105 , A61K31/713 , A61K45/06 , C12N2310/113 , C12N2310/14 , C12N2310/141 , C12N2310/3231

摘要： The present invention relates to the involvement of miR function in the development of age-related macular degeneration (AMD). It is shown that miR-23, miR-24 and/or miR-27 are involved in pathologic neovascularization in AMD, and that agonism (miR-24) and inhibition (miR23/27) of the function of these molecules blocks events contributing to development and progression of disease.