发明申请
- 专利标题： POLYNUCLEOTIDES ENCODING ANTIBODIES
- 专利标题（中）： 多核苷酸编码抗体
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申请号： US14576278申请日： 2014-12-19
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公开(公告)号： US20150099278A1公开(公告)日： 2015-04-09
- 发明人: Brenda L. Stevens , Alison Witte , Mark W. Rixon , Josephine M. Cardarelli , Thomas D. Kempe , Scott R. Presnell , Mohan Srinivasan , Susan C. Wong , Guodong Chen , Hui Wei , Stanley R. Krystek , Lumelle A. Schneeweis , Paul O. Sheppard , Indrani Chakraborty
- 申请人： Bristol-Myers Squibb Company
- 主分类号： C07K16/24
- IPC分类号： C07K16/24
摘要：
The present invention relates to antagonizing the activity of IL-17A, IL-17F and IL-23 using bispecific antibodies that comprise a binding entity that is cross-reactive for IL-17A and IL-17F and a binding entity that binds IL-23p19. The present invention relates to novel bispecific antibody formats and methods of using the same.
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