发明申请
US20150111775A1 GENETIC POLYMORPHISMS ASSOCIATED WITH CARDIOVASCULAR DISORDERS AND DRUG RESPONSE, METHODS OF DETECTION AND USES THEREOF
审中-公开
与心血管疾病相关的遗传多态性与药物反应，检测方法及其用途
- 专利标题： GENETIC POLYMORPHISMS ASSOCIATED WITH CARDIOVASCULAR DISORDERS AND DRUG RESPONSE, METHODS OF DETECTION AND USES THEREOF
- 专利标题（中）： 与心血管疾病相关的遗传多态性与药物反应，检测方法及其用途
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申请号： US14479916申请日： 2014-09-08
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公开(公告)号： US20150111775A1公开(公告)日： 2015-04-23
- 发明人: Olga IAKOUBOVA , James J. DEVLIN
- 申请人： Celera Corporation
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The present invention is based on the discovery of genetic polymorphisms that are associated with cardiovascular disorders, particularly acute coronary events such as myocardial infarction and stroke, and genetic polymorphisms that are associated with responsiveness of an individual having a cardiovascular disorder to treatment of the disorder with statin. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
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