Invention Application
- Patent Title: Insulin-Like Growth Factor-1 Receptor Inhibitors
- Patent Title (中): 胰岛素样生长因子-1受体抑制剂
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Application No.: US14387935Application Date: 2013-03-14
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Publication No.: US20150119394A1Publication Date: 2015-04-30
- Inventor: Abhijit Roychowdhury , Rajiv Sharma , Malcolm Mascarenhas , Chandrika B-Rao , Shashikant M. Patil , Sambhaji Chavan , Nitin Lad , Smriti Khanna , Christopher J. Dinsmore
- Applicant: Merck Sharp & Dohme Corp. , Piramal Enterprises Limited
- International Application: PCT/US13/31155 WO 20130314
- Main IPC: C07D413/12
- IPC: C07D413/12 ; C07D413/14
Abstract:
The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating Insulin-Like-Growth Factor I Receptor and Insulin Receptor. The compounds of the instant invention possess a core structure that comprises a sulfonyl indole moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
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