发明申请
US20150119698A1 Compositions Comprising Near-Infrared Fluorescent Particles And Uses Thereof For Imaging Activated Immune Cells In the CNS
审中-公开
包含近红外荧光颗粒的组合物及其在CNS中成像激活的免疫细胞的用途
- 专利标题: Compositions Comprising Near-Infrared Fluorescent Particles And Uses Thereof For Imaging Activated Immune Cells In the CNS
- 专利标题(中): 包含近红外荧光颗粒的组合物及其在CNS中成像激活的免疫细胞的用途
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申请号: US14584460申请日: 2014-12-29
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公开(公告)号: US20150119698A1公开(公告)日: 2015-04-30
- 发明人: Sara Eyal , Shlomo Magdassi , Emma Portnoy , Jacob Zauberman , Boris Polyak , Jacob Golenser , Yael Mardor , Dana Ekstein
- 申请人: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. , Hadasit Medical Research Services and Development Ltd. , Tel Hashomer Medical Research, Infrastructure And Service Ltd. , Drexel University
- 主分类号: A61K49/00
- IPC分类号: A61K49/00 ; A61B5/00 ; A61B5/055
摘要:
Pharmaceutical composition including nanoparticles configured for enhanced phagocytosis by phagocytic cells and labeled with a near-infrared (NIR) fluorescent probe bound to the outer surface thereof, and uses thereof in the detection of activated immune cells in the central nervous system (CNS) of a subject.
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