Invention Application
US20150175544A1 MULTICOMPONENT CRYSTALLINE SYSTEM COMPRISING DEFERASIROX AND ISONICOTINAMIDE AND A PROCESS FOR THE PREPARATION THEREOF
有权
包含DEFERASIROX和异烟肼的多组分结晶体系及其制备方法
- Patent Title: MULTICOMPONENT CRYSTALLINE SYSTEM COMPRISING DEFERASIROX AND ISONICOTINAMIDE AND A PROCESS FOR THE PREPARATION THEREOF
- Patent Title (中): 包含DEFERASIROX和异烟肼的多组分结晶体系及其制备方法
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Application No.: US14415875Application Date: 2013-08-05
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Publication No.: US20150175544A1Publication Date: 2015-06-25
- Inventor: Andreas Hafner , Fritz Blatter , Eva Roedel , Martin Szelagiewicz , Tiziana Chiodo , Tobias Hintermann , Beate Salvador , Marcus Vossen
- Applicant: BASF SE
- Applicant Address: DE Ludwigshafen
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE Ludwigshafen
- Priority: EP12179346.7 20120806
- International Application: PCT/EP2013/066360 WO 20130805
- Main IPC: C07D213/81
- IPC: C07D213/81 ; C07D249/08
Abstract:
The present invention refers to a multicomponent crystalline system (co-crystal) comprising a compound of formula (1) (4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid; INN: Deferasirox) formula (1) and a compound of formula (2) (Isonicotinamide; pyridine-4-carboxamide) formula (2), as well as to a process for obtaining the same.
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