Invention Application
US20150209418A1 MODIFIED BETA-LACTAMASES AND METHODS AND USES RELATED THERETO
有权
改性的BETA-LACTAMASES及其相关方法和用途
- Patent Title: MODIFIED BETA-LACTAMASES AND METHODS AND USES RELATED THERETO
- Patent Title (中): 改性的BETA-LACTAMASES及其相关方法和用途
-
Application No.: US14676559Application Date: 2015-04-01
-
Publication No.: US20150209418A1Publication Date: 2015-07-30
- Inventor: Pertti Koski , Ulla Airaksinen , Katja Valimaki
- Applicant: Synthetic Biologics, Inc.
- Priority: FI20105572 20100524
- Main IPC: A61K38/50
- IPC: A61K38/50 ; C12N9/86
Abstract:
The present invention relates to pharmaceuticals and modified beta-lactamases. Specifically, the invention relates to novel recombinant beta-lactamases and pharmaceutical compositions comprising the beta-lactamases. Also, the present invention relates to methods for modifying a beta-lactamase, producing the beta-lactamase and treating or preventing beta-lactam antibiotic induced adverse effects. Furthermore, the present invention relates to the beta-lactamase for use as a medicament and to the use of the beta-lactamase in the manufacture of a medicament for treating or preventing beta-lactam antibiotics induced adverse effects.Still further, the invention relates to a polynucleotide and a host cell comprising the polynucleotide.
Public/Granted literature
- US09301996B2 Modified beta-lactamases and methods and uses related thereto Public/Granted day:2016-04-05
Information query
IPC分类:
