发明申请
- 专利标题： BENZOMORPHAN COMPOUNDS AS OPIOID RECEPTORS MODULATORS
- 专利标题（中）： 作为阿片受体调节剂的苯并噻喃化合物
-
申请号： US14400129申请日： 2013-05-10
-
公开(公告)号： US20150210646A1公开(公告)日： 2015-07-30
- 发明人: Jae Hyun Park , David Rosen , Laykea Tafesse , Jianming Yu
- 申请人： Purdue Pharma L.P.
- 国际申请： PCT/IB2013/000948 WO 20130510
- 主分类号： C07D221/26
- IPC分类号： C07D221/26 ; C07D221/28 ; C07D405/06
摘要：
The present invention is directed to Benzomorphan Analog compounds of the Formula (I), Formula (IA), Formula (IB), Formula (IC), or Formula (ID) as shown below, wherein R1, R2a, R2b, R3, R4, Z, and G are as defined herein. Compounds of the Invention are useful for treating pain, constipation, and other conditions modulated by activity of opioid and ORL-1 receptors.