Invention Application
US20150218102A1 6-HETEROARYLOXY- OR 6-ARYLOXY-QUINOLINE-2-CARBOXAMIDES AND METHOD OF USE
有权
6-异亮氨酸或6-芳基喹啉-2-羧酸酰胺及其使用方法
- Patent Title: 6-HETEROARYLOXY- OR 6-ARYLOXY-QUINOLINE-2-CARBOXAMIDES AND METHOD OF USE
- Patent Title (中): 6-异亮氨酸或6-芳基喹啉-2-羧酸酰胺及其使用方法
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Application No.: US14613579Application Date: 2015-02-04
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Publication No.: US20150218102A1Publication Date: 2015-08-06
- Inventor: Andrew Bogdan , Marlon D. Cowart , David A. DeGoey , Tammie K. Jinkerson , John R. Koenig , Michael E. Kort , Bo Liu , Mark A. Matulenko , Derek W. Nelson , Meena V. Patel , Hillary Peltier , Marc J. Scanio , Brian D. Wakefield
- Applicant: AbbVie Inc.
- Main IPC: C07D215/48
- IPC: C07D215/48 ; C07D409/14 ; C07D487/08 ; C07D471/04 ; C07D487/04 ; C07D405/14 ; C07D417/14 ; C07D401/12 ; C07D401/14
Abstract:
Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein R1, R2, and R3 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Nav1.7 and/or Nav1.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
Public/Granted literature
- US09452986B2 6-heteroaryloxy- or 6-aryloxy-quinoline-2-carboxamides and method of use Public/Granted day:2016-09-27
Information query
