发明申请
US20150218138A1 PYRIDYL-AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE- AND FURANE-DERIVATIVES AS KINASE INHIBITORS
审中-公开
吡啶并吡啶基取代的吡咯，噻吩和呋喃衍生物作为激酶抑制剂
- 专利标题： PYRIDYL-AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE- AND FURANE-DERIVATIVES AS KINASE INHIBITORS
- 专利标题（中）： 吡啶并吡啶基取代的吡咯，噻吩和呋喃衍生物作为激酶抑制剂
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申请号： US14688207申请日： 2015-04-16
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公开(公告)号： US20150218138A1公开(公告)日： 2015-08-06
- 发明人: Ermes Vanotti , Marina Caldarelli , Alessandra Cirla , Barbara Forte , Antonella Ermoli , Maria Menichincheri , Antonio Pillan , Alessandra Scolaro
- 申请人： NERVIANO MEDICAL SCIENCES S.R.L.
- 申请人地址： IT Nerviano (MI)
- 专利权人： NERVIANO MEDICAL SCIENCES S.R.L.
- 当前专利权人： NERVIANO MEDICAL SCIENCES S.R.L.
- 当前专利权人地址： IT Nerviano (MI)
- 优先权： EP06111766.9 20060327
- 主分类号： C07D409/14
- IPC分类号： C07D409/14 ; A61K31/4439 ; C07D401/14 ; A61K31/4725 ; A61K31/4545 ; A61N5/10 ; A61K31/506 ; A61K31/496 ; C07D409/04 ; C07D405/04 ; A61K31/5377 ; A61K45/06 ; C07D401/04 ; C07D403/04
摘要：
The present invention provides compounds of the formula (I), or the pharmaceutically acceptable salts thereof, wherein G, W, R2, R3, R4, R5 and R6 are as defined in the specification. Further objects of the invention are processes and intermediates for the preparation of the compounds of the formula (I), pharmaceutical compositions comprising them and methods for treating cell proliferative disorders. As a matter of fact, the compounds of the formula (I) are useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.