发明申请
- 专利标题: GENE KNOCK-IN NON-HUMAN ANIMAL
- 专利标题(中): 基因无缝非人动物
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申请号: US14427355申请日: 2013-09-13
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公开(公告)号: US20150225481A1公开(公告)日: 2015-08-13
- 发明人: Koichi Jishage , Otoya Ueda
- 申请人: CHUGAI SEIYAKU KABUSHIKI KAISHA
- 申请人地址: JP Tokyo
- 专利权人: CHUGAI SEIYAKU KABUSHIKI KAISHA
- 当前专利权人: CHUGAI SEIYAKU KABUSHIKI KAISHA
- 当前专利权人地址: JP Tokyo
- 优先权: JP2012-201299 20120913
- 国际申请: PCT/JP2013/074882 WO 20130913
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61K49/00 ; G01N33/68 ; A01K67/027
摘要:
The present invention provides a non-human animal in which a DNA comprising an hp7 sequence-encoding DNA and a poly A addition signal-encoding DNA added on the 3′ side of a DNA encoding an arbitrary foreign gene is inserted in the same reading frame as that of an arbitrary target gene present on the genome of the non-human animal.
公开/授权文献
- US10822420B2 Gene knock-in non-human animal 公开/授权日:2020-11-03
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