Methods and systems are disclosed for digital control for regulation of program voltages for non-volatile memory (NVM) systems. The disclosed embodiments dynamically adjust program voltages based upon parameters associated with the cells to be programmed in order to account for IR (current-resistance) voltage drops that occur within program voltage distribution lines. Other voltage variations can also be accounted for with these dynamic adjustments, as well. The parameters for cells to be programmed can include, for example, cell address locations for the cells to be programmed, the number of cells to be programmed, and/or other desired parameters associated with the cells to be programmed. The disclosed embodiments use digital control values obtained from lookup tables based upon the cell parameters to adjust output voltages generated by voltage generation circuit blocks used to program the selected cells thereby tuning the program output voltage level to a predetermined desired level.