Invention Application
- Patent Title: Multifunctional Oral Vaccine Based on Chromosome Recombineering
- Patent Title (中): 基于染色体重组的多功能口服疫苗
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Application No.: US14428870Application Date: 2013-09-16
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Publication No.: US20150238591A1Publication Date: 2015-08-27
- Inventor: Madushini Nirosha Dharmasena , Dennis J. Kopecko
- Applicant: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV
- International Application: PCT/US2013/059980 WO 20130916
- Main IPC: A61K39/112
- IPC: A61K39/112 ; C07K14/255 ; C12N1/20 ; C07K14/25
Abstract:
A recombineered Salmonella typhi Ty21a, compositions and vaccines comprising such a Ty21a, and a method for recombineering comprising inserting a large antigenic region into a bacterial chromosome for the purpose of making multivalent vaccines to protect against one or more disease agents are described herein.
Public/Granted literature
- US09750793B2 Multifunctional oral vaccine based on chromosome recombineering Public/Granted day:2017-09-05
Information query
