- 专利标题: MONOCLONAL ANTIBODIES AGAINST ORTHOPOXVIRUSES
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申请号: US14663168申请日: 2015-03-19
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公开(公告)号: US20150252098A1公开(公告)日: 2015-09-10
- 发明人: Zhaochun CHEN , Patricia EARL , Bernard MOSS , Suzanne U. EMERSON , Robert H. PURCELL
- 申请人: The USA, as represented by the Secretary, Dept. of Health and Human Services
- 主分类号: C07K16/08
- IPC分类号: C07K16/08 ; G01N33/569
摘要:
The present invention relates to monoclonal antibodies that bind or neutralize Orthopoxviruses. The invention provides such antibodies, fragments of such antibodies retaining B5 or A33 binding ability, fully human antibodies retaining B5 or A33 binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Additionally, the invention provides for prophylactic, therapeutic, and diagnostic methods employing the antibodies and nucleic acids of the invention.
公开/授权文献
- US09708392B2 Monoclonal antibodies against orthopoxviruses 公开/授权日:2017-07-18