Invention Application
US20150274671A1 GUANIDINE AND AMINE SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS AS FACTOR XIA INHIBITORS
有权
胍胺和胺取代的四氢喹啉化合物作为因子XIA抑制剂
- Patent Title: GUANIDINE AND AMINE SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS AS FACTOR XIA INHIBITORS
- Patent Title (中): 胍胺和胺取代的四氢喹啉化合物作为因子XIA抑制剂
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Application No.: US14434764Application Date: 2013-10-11
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Publication No.: US20150274671A1Publication Date: 2015-10-01
- Inventor: Donald J. P. Pinto , Charles G. Clark , Michael J. Orwat , Leon M. Smith II , William R. Ewing
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- International Application: PCT/US13/64441 WO 20131011
- Main IPC: C07D217/04
- IPC: C07D217/04 ; C07D409/04 ; C07D405/04 ; C07D401/04
Abstract:
The present invention provides compounds of Formula (I): (Formula (I)) or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments.
Public/Granted literature
- US09403774B2 Guanidine and amine substituted tetrahydroisoquinoline compounds as factor xia inhibitors Public/Granted day:2016-08-02
Information query
