发明申请
US20150274672A1 SUBSTITUTED SPIROPIPERIDINYL COMPOUNDS USEFUL AS GPR120 AGONISTS
有权
替代的螺旋磷酸化合物可用作GPR120激动剂
- 专利标题： SUBSTITUTED SPIROPIPERIDINYL COMPOUNDS USEFUL AS GPR120 AGONISTS
- 专利标题（中）： 替代的螺旋磷酸化合物可用作GPR120激动剂
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申请号： US14434524申请日： 2013-10-11
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公开(公告)号： US20150274672A1公开(公告)日： 2015-10-01
- 发明人: Mariappan Chelliah , Hong Dong Chu , Jason M. Cox , John S. Debenham , Keith Eagen , Ping Lan , Clare London , Michael A. Plotkin , Unmesh Shah , Christopher Joseph Sinz , Zhongxiang Sun , Henry M. Vaccaro , Srikanth Venkatraman
- 申请人： Mariappan CHELLIAH , Hong Dong CHU , Jason M. COX , John S. DEBENHAM , Keith EAGEN , Ping LAN , Clare LONDON , Michael A. PLOTKIN , Unmesh SHAH , Christopher Joseph SINZ , Zhongxiang SUN , Henry M. VACCARO , Skikanth KATRAMAN , MERCK SHARP & DOHME CORP.
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 国际申请： PCT/US13/64472 WO 20131011
- 主分类号： C07D221/20
- IPC分类号： C07D221/20 ; C07D401/04 ; C07D491/107 ; C07D405/10
摘要：
The present invention relates to a compound represented by formula (I): and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing diabetes, hyperlipidemia, obesity, inflammation related disorders, and related diseases and conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR120. Pharmaceutical compositions and methods of treatment are also included.