Invention Application
US20150274672A1 SUBSTITUTED SPIROPIPERIDINYL COMPOUNDS USEFUL AS GPR120 AGONISTS
有权
替代的螺旋磷酸化合物可用作GPR120激动剂
- Patent Title: SUBSTITUTED SPIROPIPERIDINYL COMPOUNDS USEFUL AS GPR120 AGONISTS
- Patent Title (中): 替代的螺旋磷酸化合物可用作GPR120激动剂
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Application No.: US14434524Application Date: 2013-10-11
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Publication No.: US20150274672A1Publication Date: 2015-10-01
- Inventor: Mariappan Chelliah , Hong Dong Chu , Jason M. Cox , John S. Debenham , Keith Eagen , Ping Lan , Clare London , Michael A. Plotkin , Unmesh Shah , Christopher Joseph Sinz , Zhongxiang Sun , Henry M. Vaccaro , Srikanth Venkatraman
- Applicant: Mariappan CHELLIAH , Hong Dong CHU , Jason M. COX , John S. DEBENHAM , Keith EAGEN , Ping LAN , Clare LONDON , Michael A. PLOTKIN , Unmesh SHAH , Christopher Joseph SINZ , Zhongxiang SUN , Henry M. VACCARO , Skikanth KATRAMAN , MERCK SHARP & DOHME CORP.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- International Application: PCT/US13/64472 WO 20131011
- Main IPC: C07D221/20
- IPC: C07D221/20 ; C07D401/04 ; C07D491/107 ; C07D405/10
Abstract:
The present invention relates to a compound represented by formula (I): and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing diabetes, hyperlipidemia, obesity, inflammation related disorders, and related diseases and conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR120. Pharmaceutical compositions and methods of treatment are also included.
Public/Granted literature
- US09708270B2 Substituted spiropiperidinyl compounds useful as GPR120 agonists Public/Granted day:2017-07-18
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