Invention Application
US20150291509A1 NOVEL BIPHENYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES OR AUTOIMMUNE DISEASES COMPRISING THE SAME AS ACTIVE INGREDIENT
有权
新颖的联苯衍生物或药物可接受的盐，以及用于预防或治疗包含其作为活性成分的炎症性疾病或自身免疫性疾病的药物组合物
- Patent Title: NOVEL BIPHENYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES OR AUTOIMMUNE DISEASES COMPRISING THE SAME AS ACTIVE INGREDIENT
- Patent Title (中): 新颖的联苯衍生物或药物可接受的盐，以及用于预防或治疗包含其作为活性成分的炎症性疾病或自身免疫性疾病的药物组合物
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Application No.: US14237256Application Date: 2012-08-06
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Publication No.: US20150291509A1Publication Date: 2015-10-15
- Inventor: Chang Hoon Lee , Kyeong Lee
- Applicant: Chang Hoon Lee , Kyeong Lee
- Applicant Address: KR Seoul
- Assignee: Dongguk University Industry-Academic Cooperation Foundation
- Current Assignee: Dongguk University Industry-Academic Cooperation Foundation
- Current Assignee Address: KR Seoul
- Priority: KR10-2011-0078076 20110805
- International Application: PCT/KR2012/006233 WO 20120806
- Main IPC: C07C233/47
- IPC: C07C233/47 ; C07D295/195
Abstract:
The present invention relates to a novel biphenyl derivative or a pharmaceutically acceptable salt thereof, a pharmaceutical composition for preventing or treating inflammatory diseases or autoimmune diseases comprising the same as an active ingredient, and methods for treating inflammatory disease or autoimmune diseases with the pharmaceutical composition. Novel biphenyl derivatives according to the present invention promote the phagocytosis of macrophages and inhibit the chemotaxis to exhibit excellent inflammation terminating and anti-inflammatory effects and thus can be effectively used as therapeutic agents for inflammatory diseases or autoimmune diseases.
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