公开(公告)号：US12013640B2

公开(公告)日：2024-06-18

申请号：US17329767

申请日：2021-05-25

申请人： SHIN-ETSU CHEMICAL CO., LTD.

发明人： Takayoshi Nakahara ,  Takeru Watanabe ,  Daisuke Kori ,  Yusuke Biyajima ,  Tsutomu Ogihara

IPC分类号： G03F7/11 ,  C07C233/18 ,  C07C233/47 ,  C07C233/55 ,  C07D251/34 ,  C07D487/04 ,  C08F38/00 ,  C09D149/00 ,  G03F7/09

CPC分类号： G03F7/11 ,  C07C233/18 ,  C07C233/47 ,  C07C233/55 ,  C07D251/34 ,  C07D487/04 ,  C08F38/00 ,  C09D149/00 ,  G03F7/094 ,  C07C2603/18

摘要： A resist underlayer film material used in multilayer resist method contains (A) compound shown by following general formula (1), and (B) organic solvent, where X independently represents monovalent organic group shown by following general formula (2); W contains an “m” number of partial structures each independently shown by following formula (3); “m” and “n” each represent an integer of 1 to 10; broken lines represent bonding arms; Z represents aromatic group; A represents single bond or —O—(CH2)p—; “k” represents integer of 1 to 5; “p” represents integer of 1 to 10; R01 represents hydrogen atom or monovalent organic group having 1 to 10 carbon atoms. Material is capable of forming resist underlayer film excellent in planarizing property in fine patterning process by multilayer resist method in semiconductor-device manufacturing process; and patterning processes and methods for forming resist underlayer film use material.

公开(公告)号：US20240192236A1

公开(公告)日：2024-06-13

申请号：US18523548

申请日：2023-11-29

申请人： ARK Diagnostics, Inc.

发明人： Johnny Jose Valdez ,  Byung Sook Moon ,  Michael Kevin Helms ,  Alejandro A. Orozco

IPC分类号： G01N33/94 ,  A61K39/00 ,  C07C229/28 ,  C07C233/36 ,  C07C233/47 ,  C07C321/04 ,  C07C323/25 ,  C07K16/44 ,  G01N33/53

CPC分类号： G01N33/9473 ,  C07C229/28 ,  C07C233/36 ,  C07C233/47 ,  C07C321/04 ,  C07C323/25 ,  C07K16/44 ,  G01N33/53 ,  G01N33/5308 ,  A61K2039/505 ,  A61K2039/60 ,  C07C2601/12 ,  C07C2601/14

摘要： Compounds and methods for use in detecting gabapentin in a sample suspected of containing gabapentin are disclosed. Gabapentin derivatives are used to produce gabapentin conjugates. A gabapentin-immunogenic carrier conjugate may be used as an immunogen for the preparation of an anti-gabapentin antibody. A gabapentin-detectable label may be used in a signal producing system in gabapentin assays.

公开(公告)号：US11981695B2

公开(公告)日：2024-05-14

申请号：US17059361

申请日：2019-05-27

申请人： UNIVERSITÉ DE BOURGOGNE ,  INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)

发明人： Naim Khan ,  Sylvain Juge ,  Aziz Hichami ,  Jérôme Bayardon ,  Marie-Laure Louillat-Habermeyer ,  Baptiste Rugeri

IPC分类号： A23K20/158 ,  A23L33/00 ,  A23L33/12 ,  A61P3/04 ,  C07C233/47 ,  C07D263/16 ,  C07D303/16 ,  C07D305/06 ,  C07D307/12 ,  C07D319/06 ,  C07F9/40

CPC分类号： C07F9/4015 ,  A23K20/158 ,  A23L33/12 ,  A23L33/40 ,  A61P3/04 ,  C07C233/47 ,  C07D263/16 ,  C07D303/16 ,  C07D305/06 ,  C07D307/12 ,  C07D319/06 ,  A23V2002/00

摘要： Disclosed is a linoleic acid derivative of Formula (I) below including a hydrophobic part C17H31 linked to a polar head part “A”:






wherein the polar head part A is selected from A1 to A4 below:










or a pharmaceutically/food quality acceptable salt thereof.

公开(公告)号：US11832638B2

公开(公告)日：2023-12-05

申请号：US16838192

申请日：2020-04-02

申请人： GIVAUDAN SA

发明人： Feng Shi ,  Harry Renes ,  Esther Van Ommeren ,  Susanna Magdalena Vorster ,  Yili Wang ,  Adri De Klerk ,  Chris Winkel

IPC分类号： A23L2/39 ,  A23C9/13 ,  A23C9/156 ,  A23C11/10 ,  A23C19/09 ,  A23L2/56 ,  C07C233/47 ,  C07C233/49 ,  C12G3/06 ,  C12C5/02 ,  A23F5/24 ,  A23C15/16 ,  A23L7/161 ,  A23L27/21 ,  A23L19/18 ,  A23L27/60 ,  A23L27/20 ,  C07C321/14 ,  A23L27/50 ,  A23L23/10 ,  A23L19/20 ,  A23L11/50 ,  A23L11/65 ,  A21D13/41 ,  A23L23/00 ,  A23L7/196 ,  A23L13/50 ,  A23C13/12 ,  A23C15/12 ,  A23F5/46 ,  A23L2/02

CPC分类号： A23L2/39 ,  A23C9/1307 ,  A23C9/156 ,  A23C11/103 ,  A23C15/16 ,  A23C19/0904 ,  A23C19/0925 ,  A23F5/243 ,  A23L2/56 ,  A23L7/161 ,  A23L11/50 ,  A23L11/65 ,  A23L19/18 ,  A23L19/20 ,  A23L23/10 ,  A23L27/202 ,  A23L27/21 ,  A23L27/50 ,  A23L27/60 ,  C07C233/47 ,  C07C233/49 ,  C07C321/14 ,  C12C5/026 ,  C12G3/06 ,  A21D13/41 ,  A23C13/12 ,  A23C15/12 ,  A23F5/465 ,  A23L2/02 ,  A23L7/196 ,  A23L13/50 ,  A23L23/00 ,  A23V2002/00

摘要： A flavour composition comprising a compound according to the formula (I) edible salts thereof, wherein R1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and m is 0 or 1.

公开(公告)号：US11623943B2

公开(公告)日：2023-04-11

申请号：US17196167

申请日：2021-03-09

申请人： API CORPORATION

发明人： Masaki Nagahama

IPC分类号： A61K31/165 ,  C07K5/062 ,  C07B57/00 ,  C07C231/12 ,  C07C231/20 ,  C07C237/06 ,  C07C233/47 ,  C07C231/02

摘要： The present invention provides a method of industrially and safely producing lacosamide high in diastereomeric excess at a high yield and a low cost. Adopting a particular isomerization-crystallization condition makes it possible to a method of industrially and safely producing lacosamide high in diastereomeric excess at a high yield and a low cost. Additionally, an intermediate efficacious for producing lacosamide is provided.

公开(公告)号：US20220409536A1

公开(公告)日：2022-12-29

申请号：US17278040

申请日：2019-09-19

申请人： ModernaTX, Inc.

发明人： Kerry E. BENENATO ,  Mark CORNEBISE ,  Edward HENNESSY

IPC分类号： A61K9/127 ,  A61K47/10 ,  A61K47/28 ,  A61K47/24 ,  A61K31/7105 ,  A61K31/573 ,  A61K31/519 ,  A61K31/167 ,  A61K45/06 ,  C07C229/12 ,  C07C229/16 ,  C07D239/54 ,  C07D239/47 ,  C07D473/34 ,  C07C233/47 ,  C07C275/14 ,  C07C335/08 ,  C07D233/61 ,  C07C311/05 ,  C07D473/18 ,  C07C229/14 ,  C07C311/64 ,  C07D249/04 ,  C07D209/48 ,  C07D295/13 ,  C07C279/36 ,  C07C279/28 ,  C07C215/08 ,  C07C235/10 ,  C07F9/09 ,  C07C311/14

摘要： The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.

公开(公告)号：US11524933B2

公开(公告)日：2022-12-13

申请号：US16887367

申请日：2020-05-29

申请人： Givaudan SA

发明人： Feng Shi ,  Harry Renes ,  Esther Van Ommeren ,  Susanna Magdalena Vorster ,  Yili Wang ,  Adri De Klerk ,  Xiaogen Yang

IPC分类号： C07C235/74 ,  A23L2/56 ,  C07C233/47 ,  C07C233/49 ,  C07C233/52 ,  C07D207/16 ,  A23C9/13 ,  A23C9/156 ,  A23C11/10 ,  A23C15/12 ,  A23C19/09 ,  C12G3/06 ,  C12C5/02 ,  A23L27/20 ,  A23L27/50 ,  A23L27/60 ,  A23L23/10 ,  A23F5/24 ,  A23L19/18 ,  A23L27/21 ,  C07C323/59 ,  A23L19/20 ,  A23L7/161 ,  C07C237/22 ,  A23L11/50 ,  A23L11/65 ,  C07C233/18 ,  A23L23/00 ,  A23L13/50 ,  A23C13/12 ,  A23F5/46

摘要： A flavour composition comprising a compound according to the formula (I) or edible salts thereof, wherein R1 is alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R1 together with the carbonyl to which it is attached is a residue carboxylic acid, and NR2R3, in which R3 is H or together with R2 and the N-atom to which they are attached, a 5-membered ring, is a residue of an amino acid, in particular proteinogenic amino acid, ornithine, gamma-aminobutyric acid or beta alanine, or a 1-amino cycloalkyl carboxylic acid.

公开(公告)号：US11472918B2

公开(公告)日：2022-10-18

申请号：US16791133

申请日：2020-02-14

申请人： Rutgers, The State University of New Jersey

发明人： Joachim B. Kohn ,  Durgadas Bolikal ,  Julian Chesterman ,  Jarrod Cohen

IPC分类号： C08G63/64 ,  C07C59/68 ,  C07C59/52 ,  C07C69/732 ,  C07C69/40 ,  C07C69/36 ,  A61L31/06 ,  A61K47/34 ,  A61L31/16 ,  C07C233/47 ,  A61L31/18 ,  A61L31/14 ,  C08G67/00 ,  C07C69/96 ,  C07C69/736 ,  C08G63/66

摘要： The present invention provides new classes of phenol compounds, including those derived from tyrosol and analogues, useful as monomers for preparation of biocompatible polymers, and biocompatible polymers prepared from these monomeric phenol compounds, including novel biodegradable and/or bioresorbable polymers. These biocompatible polymers or polymer compositions with enhanced bioresorbabilty and processibility are useful in a variety of medical applications, such as in medical devices and controlled-release therapeutic formulations. The invention also provides methods for preparing these monomeric phenol compounds and biocompatible polymers.

公开(公告)号：US11471791B2

公开(公告)日：2022-10-18

申请号：US15779714

申请日：2016-11-08

申请人： HINDUSTAN PETROLEUM CORPORATION LIMITED

发明人： Raman Ravishankar ,  Chinthalapati Sivakesava Raju ,  Jitalaxmi Bharali ,  Sheshachala Srinivasa Narasimha ,  Peddy Venkat Chalapathi Rao ,  Nettem Venkateswarlu Choudary

IPC分类号： B01D17/04 ,  B09C1/08 ,  C02F1/68 ,  C07C233/47 ,  C07C323/59 ,  E02B15/04 ,  E02B15/10 ,  C02F101/32 ,  C02F103/00 ,  C02F103/08

摘要： A process is provided for separating hydrophobic material from a mixture of hydrophobic and hydrophilic material using peptide-based amphiphilic organogelators.

公开(公告)号：US11365183B2

公开(公告)日：2022-06-21

申请号：US16363022

申请日：2019-03-25

申请人： MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN ,  BOARD OF REGENTS OF UNIVERSITY OF TEXAS SYSTEM

发明人： Wolf-Hagen Schunck ,  Gerd Wallukat ,  Robert Fischer ,  Cosima Arnold ,  Dominik N. Mueller ,  Narender Puli ,  John R. Falck

IPC分类号： C07D303/38 ,  C07C235/76 ,  C07C275/20 ,  C07C233/09 ,  C07C233/49 ,  C07C275/14 ,  C07C233/47 ,  C07C275/16 ,  C07C235/28

摘要： The present invention provides compounds (n-3 PUFA derivatives) of formula (I): that modulate conditions associated with cardiac damage, especially cardiac arrhythmias.