发明申请
- 专利标题： SALTS OF PRODRUGS OF PIPERAZINE AND SUBSTITUTED PIPERIDINE ANTIVIRAL AGENTS
- 专利标题（中）： 哌嗪和替代哌啶抗病毒药物的产品
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申请号： US14800315申请日： 2015-07-15
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公开(公告)号： US20150315218A1公开(公告)日： 2015-11-05
- 发明人: Yasutsugu Ueda , Timothy P. Connolly , John F. Kadow , Nicholas A. Meanwell , Tao Wang , Chung-Pin H. Chen , Kap-Sun Yeung , Zhongxing Zhang , David Kenneth Leahy , Shawn K. Pack , Nachimuthu Soundararajan , Pierre Sirard , Kathia Levesque , Dominique Thoraval
- 申请人： Bristol-Myers Squibb Company
- 主分类号： C07F9/6561
- IPC分类号： C07F9/6561
摘要：
This invention provides for prodrug Compounds I, pharmaceutical compositions thereof, and their use in treating HIV infection: wherein: X is C or N with the proviso that when X is N, R1 does not exist; W is C or N with the proviso that when W is N, R2 does not exist; V is C; E is hydrogen or a pharmaceutically acceptable salt thereof; and Y is selected from the group consisting of wherein: L and M are independently selected from the group consisting of C1-C6 alkyl, phenyl, benzyl, trialkylsilyl, -2,2,2-trichloroethoxy and 2-trimethylsilylethoxy.
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