Invention Application
US20150320783A1 N-METHYLSEROTONIN AND RELATED SUBSTANCES FOR USE IN TREATING / LESSENING THE OCCURRENCE OF HOT FLASHES RELATED TO MENOPAUSE
审中-公开
N-甲基硅氧烷和相关物质用于治疗/感染与MENOPAUSE相关的热闪烁事件
- Patent Title: N-METHYLSEROTONIN AND RELATED SUBSTANCES FOR USE IN TREATING / LESSENING THE OCCURRENCE OF HOT FLASHES RELATED TO MENOPAUSE
- Patent Title (中): N-甲基硅氧烷和相关物质用于治疗/感染与MENOPAUSE相关的热闪烁事件
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Application No.: US14761834Application Date: 2014-01-24
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Publication No.: US20150320783A1Publication Date: 2015-11-12
- Inventor: Christopher Michael BUTT , Michael WEISER
- Applicant: DSM IP ASSETS B.V.
- International Application: PCT/IB2014/058524 WO 20140124
- Main IPC: A61K31/7056
- IPC: A61K31/7056 ; A23L1/30 ; A61K36/758
Abstract:
Zanthoxylum piperitum (commonly known as Japanese pepper) seeds, including its mature seeds, contain the NMS precursor/V-methylserotonin 5-O-B-glucoside (“NMS-glucoside”) present in sufficient concentration and are metabolized with sufficient efficiency so as to provide an effective amount of NMS for use in amelioration of menopausal symptoms, including hot flashes/flushes. The Japanese pepper seeds or Japanese pepper seed extracts can also be used to enrich other sources of NMS or NMS precursors in order to provide a nutraceutical or food supplement for controlling hot flashes.
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