There is provided a method and device in a wireless communication system, the method comprising: a cell information interacting step of interacting information about a first cell and a second cell having interference with each other between the first cell and the second cell to determine a source cell and a target cell among the first cell and the second cell, wherein the target cell performs synchronization with the source cell being a synchronization source; an initial synchronizing step of performing initial frame-level synchronization by the target cell with the source cell being the synchronization source; a synchronization information interacting step of interacting information about a synchronization subframe position between the source cell and the target cell to determine a synchronization subframe position configurable for both the source cell and the target cell; and a symbol-level synchronizing step of performing symbol-level synchronization between the source cell and the target cell according to the determined synchronization subframe position. According to the disclosure, it is possible to realize synchronization among cells belonging to different operators and/or adopting different synchronizing manners.