Invention Application
US20150344972A1 COMPOSITIONS COMPRISING SOLUBLE CD84 OR ANTI-CD84 ANTIBODIES AND METHODS FOR DIAGNOSING AND TREATING B-CLL
审中-公开
包含可溶性CD84或抗CD84抗体的组合物和用于诊断和治疗B-CLL的方法
- Patent Title: COMPOSITIONS COMPRISING SOLUBLE CD84 OR ANTI-CD84 ANTIBODIES AND METHODS FOR DIAGNOSING AND TREATING B-CLL
- Patent Title (中): 包含可溶性CD84或抗CD84抗体的组合物和用于诊断和治疗B-CLL的方法
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Application No.: US14827337Application Date: 2015-08-17
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Publication No.: US20150344972A1Publication Date: 2015-12-03
- Inventor: Idit SHACHAR , Inbal BINSKY , Mirko SOBOTTA
- Applicant: Yeda Research and Development Co. Ltd.
- Applicant Address: IL Rehovot
- Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee Address: IL Rehovot
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/574

Abstract:
A method of diagnosing B-CLL in a subject in need thereof is provided. The method comprising determining in a biological sample of the subject a level of CD84 isoform C (SEQ ID NO: 30), wherein an increase in the level of the CD84 isoform C (SEQ ID NO: 30) beyond a predetermined threshold with respect to a level of the CD84 in a biological sample from a healthy individual is indicative of the B-CLL.
Public/Granted literature
- US10329347B2 Compositions comprising soluble CD84 or anti-CD84 antibodies and methods for diagnosing and treating B-CLL Public/Granted day:2019-06-25
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