发明申请
- 专利标题： PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA
- 专利标题（中）： 人类磷脂酰肌醇三激酶三磷酸抑制剂
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申请号： US14443294申请日： 2013-11-15
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公开(公告)号： US20150353552A1公开(公告)日： 2015-12-10
- 发明人: Abdelghani Abe Achab , Michael D. Altman , Yongqi Deng , Timothy Guzi , Solomon Kattar , Jason D. Katz , Joey L. Methot , Hua Zhou , Meredeth McGowan , Matthew P. Christopher , Yudith Garcia , Neville John Anthony , Francesc Xavier Fradera Llinas , Kin Chiu Fong , Xiansheng Leng , Changwei Mu , Sixing Zhang , Rong Zhang
- 申请人： Abdelghani Abe ACHAB , Michael D. ALTMAN , Yongqi DENG , Timothy GUZI , Solomon KATTAR , Jason D. KATZ , Joey L. METHOT , Hua ZHOU , Meredeth MCGOWAN , Matthew P. CHRISTOPHER , Yudith GARCIA , Neville John THONY , Francesc Xavier FRADERA LLINAS , Changwei MU , Sixing ZHANG , Rong ZHANG , Kin Chiu FONG , Xiansheng LENG , MERCK SHARP & DOHME CORP.
- 国际申请： PCT/CN2013/001394 WO 20131115
- 主分类号： C07D473/30
- IPC分类号： C07D473/30 ; A61K31/5377 ; A61K31/52
摘要：
The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.
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