Invention Application
US20150376709A1 METHOD FOR PREDICTION OF SPONTANEOUS PRETERM BIRTH BY MEASURING CELL FREE NUCLEIC ACIDS IN MATERNAL BLOOD
审中-公开
通过测量细胞免疫核酸在母体中预测自发性前体生物的方法
- Patent Title: METHOD FOR PREDICTION OF SPONTANEOUS PRETERM BIRTH BY MEASURING CELL FREE NUCLEIC ACIDS IN MATERNAL BLOOD
- Patent Title (中): 通过测量细胞免疫核酸在母体中预测自发性前体生物的方法
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Application No.: US14851809Application Date: 2015-09-11
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Publication No.: US20150376709A1Publication Date: 2015-12-31
- Inventor: Yafeng Dong , Carl Weiner
- Applicant: Yafeng Dong , Carl Weiner
- Main IPC: C12Q1/68
- IPC: C12Q1/68

Abstract:
A nucleic acid normalization kit can include a nucleic acid having a normalization sequence including or complementary to one or more of SEQ ID NOs: 1-4 and 301-303 or unique segment thereof, the nucleic acid being present in an amount sufficient for use in a nucleic acid normalization protocol. The normalization kit can be used in a method of identifying a pregnancy normalization nucleic acid sequence. A nucleic acid diagnostic kit for diagnosing susceptibility to preterm birth (PTB) can include a nucleic acid having a CFP RNA PTB biomarker sequence including or complementary to one or more of SEQ ID NOs: 5-300 or unique segment thereof, the nucleic acid being present in an amount sufficient for use in a nucleic acid diagnostic protocol for diagnosing susceptibility to PTB. The diagnostic kit can be used in a method for predicting susceptibility of a pregnant woman to preterm birth (PTB).
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