Invention Application
US20150376709A1 METHOD FOR PREDICTION OF SPONTANEOUS PRETERM BIRTH BY MEASURING CELL FREE NUCLEIC ACIDS IN MATERNAL BLOOD 审中-公开
通过测量细胞免疫核酸在母体中预测自发性前体生物的方法

  • Patent Title: METHOD FOR PREDICTION OF SPONTANEOUS PRETERM BIRTH BY MEASURING CELL FREE NUCLEIC ACIDS IN MATERNAL BLOOD
  • Patent Title (中): 通过测量细胞免疫核酸在母体中预测自发性前体生物的方法
  • Application No.: US14851809
    Application Date: 2015-09-11
  • Publication No.: US20150376709A1
    Publication Date: 2015-12-31
  • Inventor: Yafeng DongCarl Weiner
  • Applicant: Yafeng DongCarl Weiner
  • Main IPC: C12Q1/68
  • IPC: C12Q1/68
METHOD FOR PREDICTION OF SPONTANEOUS PRETERM BIRTH BY MEASURING CELL FREE NUCLEIC ACIDS IN MATERNAL BLOOD
Abstract:
A nucleic acid normalization kit can include a nucleic acid having a normalization sequence including or complementary to one or more of SEQ ID NOs: 1-4 and 301-303 or unique segment thereof, the nucleic acid being present in an amount sufficient for use in a nucleic acid normalization protocol. The normalization kit can be used in a method of identifying a pregnancy normalization nucleic acid sequence. A nucleic acid diagnostic kit for diagnosing susceptibility to preterm birth (PTB) can include a nucleic acid having a CFP RNA PTB biomarker sequence including or complementary to one or more of SEQ ID NOs: 5-300 or unique segment thereof, the nucleic acid being present in an amount sufficient for use in a nucleic acid diagnostic protocol for diagnosing susceptibility to PTB. The diagnostic kit can be used in a method for predicting susceptibility of a pregnant woman to preterm birth (PTB).
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