发明申请
- 专利标题： NOVEL INDOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS
- 专利标题（中）： 新型吲哚衍生物作为抗糖尿病药物有用
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申请号： US14769159申请日： 2014-03-10
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公开(公告)号： US20160002224A1公开(公告)日： 2016-01-07
- 发明人: John J. Acton, III , Rajan Anand , Ashok Arasappan , Qun Dang , Iyassu Sebhat , Zhifa Pu , Takao Suzuki
- 申请人： John J. ACTON, III , Rajan ANAND , Ashok ARASAPPAN , Qun DANG , Iyassu SEBHAT , Zhifa PU , Takao SUZUKI , MERCK SHARP & DOHME CORP.
- 国际申请： PCT/CN2014/073149 WO 20140310
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/404 ; A61K31/437 ; A61K31/4985 ; A61K31/4439 ; A61K31/366 ; A61K31/397 ; C07D209/08 ; C07D401/10
摘要：
Novel compounds of the structural formula (I) are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.
公开/授权文献
- US09650375B2 Indole derivatives useful as anti-diabetic agents 公开/授权日：2017-05-16
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