Invention Application
- Patent Title: 1,2,6-SUBSTITUTED BENZIMIDAZOLES AS FLAP MODULATORS
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Application No.: US14777492Application Date: 2014-03-13
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Publication No.: US20160039790A1Publication Date: 2016-02-11
- Inventor: Wenying Chai , Curt A. Dvorak , Wendy Eccles , James P. Edwards , Steven D. Goldberg , Paul J. Krawczuk , Alec D. Lebsack , Jing Liu , Daniel J. Pippel , Zachary S. Sales , Virginia M. Tanis , Mark S. Tichenor , John J. M. Wiener
- Applicant: Wenying CHAI , Curt A. DVORAK , Wendy ECCLES , James P. EDWARDS , Steven D. GOLDBERG , Paul J. KRAWCZUK , Alec D. LEBSACK , Jing LIU , Daniel J. PIPPEL , Zachary S. SALES , Virginia M. TANIS , Mark S. TICHENOR , John J.M. WIENER , JANSSEN PHARMACEUTICA NV
- International Application: PCT/US2014/025609 WO 20140313
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D401/14 ; C07D403/14 ; C07D403/12

Abstract:
The present invention relates to compounds of Formula (I), and solvates, hydrates, and pharmaceutically acceptable salts thereof, wherein X1, X1′, X1″, R1, R2 and R3 are as defined herein, useful as FLAP modulators. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invention.
Public/Granted literature
- US09695149B2 1,2,6-substituted benzimidazoles as flap modulators Public/Granted day:2017-07-04
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