In an implementation, a method for managing airflow distribution through a plurality of adaptive vent tiles comprises accessing a model that correlates an environmental condition with a setting arrangement of the plurality of adaptive vent tiles and operational settings of a plurality of fluid moving devices. The method also includes calculating, through implementation of the model, a setting arrangement of the plurality of adaptive vent tiles that results in a substantially optimized metric subject to a set of constraints, wherein the setting arrangement of the plurality of adaptive vent tiles comprises an arrangement in which adaptive vent tiles in respective groups of adaptive vent tiles have substantially uniform opening levels with respect to each other.