发明申请
- 专利标题: THIAZOLE-BASED INHIBITORS OF SCAVENGER RECEPTOR BI
- 专利标题(中): 螯合剂受体BI的基于噻唑的抑制剂
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申请号: US14436626申请日: 2013-10-21
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公开(公告)号: US20160060254A1公开(公告)日: 2016-03-03
- 发明人: Chris Dockendorff , Willmen Youngsaye , Partha Pratim Nag , Timothy A. Lewis , Sivaraman Dandapani , Benito Munoz , Patrick Falloon , Thomas Nieland , Monty Krieger , Miao Yu
- 申请人: Chris Dockendorff , Willmen Youngsaye , Partha Pratim Nag , Timothy A. Lewis , Sivaraman Dandapani , Benito Munoz , Patrick Falloon , Thomas Nieland , Monty Krieger , Miao Yu
- 国际申请: PCT/US2013/065988 WO 20131021
- 主分类号: C07D417/04
- IPC分类号: C07D417/04 ; C07D491/048 ; C07D417/14
摘要:
This application describes compounds and methods that can inhibit Scavenger receptor class B, type I (SR-BI) activity, which compounds and methods can used, for example, to mediate high-density lipoprotein (HDL) lipid uptake and treat hepatitis C viral infections.
公开/授权文献
- US09951055B2 Thiazole-based inhibitors of scavenger receptor BI 公开/授权日:2018-04-24
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