Devices, systems and methods are disclosed for selecting and sending one of a plurality of responses to a call on a communications device. A user may select a default response or a custom response. When the user receives a call to a communications device, a set of responses is displayed on the communications device to facilitate selection by the user. A response includes a message and a call processing command. A message is in the form of an audio clip, text message, webpage, picture, video, etc. A call processing command is performed along with the message. This plurality of responses can be organized by the user in groups associated with classes of callers, such as friends, family, co-workers, etc. In this manner, the responses available to the user when a call is received changes depending on the caller.