Invention Application
- Patent Title: Indazole Ureas and Method of Use
- Patent Title (中): 吲唑脲和使用方法
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Application No.: US14854433Application Date: 2015-09-15
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Publication No.: US20160075692A1Publication Date: 2016-03-17
- Inventor: Jerome F. Daanen , David A. DeGoey , Jennifer M. Frost , John R. Koenig , Steve Latshaw , Mark Matulenko , Marc Scanio , Lei Shi , William H. Bunnelle
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Main IPC: C07D403/14
- IPC: C07D403/14 ; C07D401/14 ; C07D405/14 ; C07D491/08 ; C07D413/14 ; C07D403/04 ; C07D417/14

Abstract:
Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein A, R1 and R2 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Nav1.7 and/or Nav1.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
Public/Granted literature
- US09783527B2 Indazole ureas and method of use Public/Granted day:2017-10-10
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