Invention Application
US20160082098A1 OUTER MEMBRANE VESICLE (OMV) VACCINE COMPRISING N. MENINGITIDIS SEROGROUP B OUTER MEMBRANE PROTEINS
审中-公开
外膜蛋白（OMV）包含N. MENINGITIDIS SEROGROUP B外膜蛋白的疫苗
- Patent Title: OUTER MEMBRANE VESICLE (OMV) VACCINE COMPRISING N. MENINGITIDIS SEROGROUP B OUTER MEMBRANE PROTEINS
- Patent Title (中): 外膜蛋白（OMV）包含N. MENINGITIDIS SEROGROUP B外膜蛋白的疫苗
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Application No.: US14961725Application Date: 2015-12-07
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Publication No.: US20160082098A1Publication Date: 2016-03-24
- Inventor: Mariagrazia PIZZA , Rino RAPPUOLI , Marzia Monica GIULIANI
- Applicant: GlaxoSmithKline Biologicals SA
- Applicant Address: BE Rixensart
- Assignee: GlaxoSmithKline Biologicals SA
- Current Assignee: GlaxoSmithKline Biologicals SA
- Current Assignee Address: BE Rixensart
- Priority: GB0001067.8 20000117; GB0005699.4 20000309
- Main IPC: A61K39/095
- IPC: A61K39/095
Abstract:
A composition comprising (a) Neisseria meningitidis serogroup B outer membrane vesicles (OMVs), and (b) an immunogenic component selected from other Neisseria proteins, or immunogenic fragments thereof. Component (b) preferably includes a protein from a different NmB strain from that from which the OMV of component (a) is derived. The OMVs are preferably obtained by deoxycholate extraction. Optionally, the composition may also comprise a protective antigen against other pathogens.
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