The purpose is to provide a protective layer transfer sheet and an intermediate transfer medium, in which the protective layer has excellent foil tearing property during transfer and in which sufficient durability can be imparted to the thermally transferred image.The above problem is solved by a protective layer transfer sheet in which a transferable protective layer (20) is provided on one surface of a substrate (1) so as to be peelable from the substrate (1), wherein the transferable protective layer (20) has a layered structure in which a first protective layer (3A), and a second protective layer (3B) which is in contact directly with the first protective layer (3A), are provided in this order from the substrate (1); the first protective layer contains an epoxy-cured resin in which a reactive resin having a functional group capable of reacting with an epoxy group and having a glass transition temperature (Tg) of not less than 60° C. is reacted with and cured by an epoxy curing agent; and the second protective layer (3B) contains a polyester resin having a number-average molecular weight (Mn) of not less than 8000 and a glass transition temperature (Tg) of not less than 45° C.