Invention Application
US20160102320A1 ADENOVIRAL VECTOR ENCODING HUMAN ATONAL HOMOLOG-1 (HATH1)
有权
编码人类神经同源异体1（HATH1）的腺病毒载体
- Patent Title: ADENOVIRAL VECTOR ENCODING HUMAN ATONAL HOMOLOG-1 (HATH1)
- Patent Title (中): 编码人类神经同源异体1（HATH1）的腺病毒载体
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Application No.: US14879318Application Date: 2015-10-09
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Publication No.: US20160102320A1Publication Date: 2016-04-14
- Inventor: Douglas E. Brough , Damodar R. Ettyreddy
- Applicant: GENVEC, INC.
- Applicant Address: US MD Gaithersburg
- Assignee: GENVEC, INC.
- Current Assignee: GENVEC, INC.
- Current Assignee Address: US MD Gaithersburg
- Main IPC: C12N15/86
- IPC: C12N15/86 ; A61K48/00 ; A61K38/16
Abstract:
The invention is directed to a replication-deficient adenoviral vector comprising a nucleic acid sequence encoding a human atonal homolog-1 (Hath1) protein operably linked to a human glial fibrillary acidic protein (GFAP) promoter. The invention also is directed to a composition and method utilizing the adenoviral vector to generate sensory cells in the inner ear of a human.
Public/Granted literature
- US09951351B2 Adenoviral vector encoding human atonal homolog-1 (HATH1) Public/Granted day:2018-04-24
Information query
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