Invention Application
- Patent Title: SUBSTITUTED TETRAHYDROPYRANS AND METHOD OF USE
- Patent Title (中): 取代的四氢呋喃和使用方法
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Application No.: US14926727Application Date: 2015-10-29
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Publication No.: US20160122331A1Publication Date: 2016-05-05
- Inventor: Philip R. Kym , Xueqing Wang , Xenia B. Searle , Bo Liu , Ming C. Yeung
- Applicant: AbbVie Inc.
- Main IPC: C07D407/12
- IPC: C07D407/12 ; A61K45/06 ; A61K31/357

Abstract:
Compounds of formula (I) and pharmaceutically acceptable salts or radiolabelled forms thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and m are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein. Methods for making the compounds are described. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
Public/Granted literature
- US09567322B2 Substituted tetrahydropyrans and method of use Public/Granted day:2017-02-14
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