Invention Application
- Patent Title: CYCLIC PHOSPHONATE SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
- Patent Title (中): 环状磷酸酯取代的核苷类衍生物及其用于治疗病毒性疾病的方法
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Application No.: US14899008Application Date: 2014-06-16
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Publication No.: US20160122380A1Publication Date: 2016-05-05
- Inventor: Stephane Bogen , Vinay Girijavallabhan , Quang Truong , Ping Chen , Frank Bennett , Angela Kerekes , Qun Dang , David B. Olsen , Ian Davies
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- International Application: PCT/US14/42463 WO 20140616
- Main IPC: C07H19/10
- IPC: C07H19/10 ; A61K45/06 ; A61K31/7072
Abstract:
The present invention relates to Cyclic Phosphonate Substituted Nucleoside Derivatives of Formula (I): (structure) and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2 and R3 are as defined herein, as well as to compositions and methods of using the Cyclic Phosphonate Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
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Information query
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