Invention Application
US20160152600A1 SYNTHESIS OF (2S,5R)-5-ETHYNYL-1-PYRROLIDINE-2-CARBONITRILE
审中-公开
（2S，5R）-5-乙基-1-吡咯烷-2-碳烯酮的合成
- Patent Title: SYNTHESIS OF (2S,5R)-5-ETHYNYL-1-PYRROLIDINE-2-CARBONITRILE
- Patent Title (中): （2S，5R）-5-乙基-1-吡咯烷-2-碳烯酮的合成
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Application No.: US15000017Application Date: 2016-01-18
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Publication No.: US20160152600A1Publication Date: 2016-06-02
- Inventor: Todd S. McDermott , Seble H. Wagaw , Kenneth M. Engstrom , Jorge Gandarilla , Albert Kruger , Michael J. Rozema , Michael G. Fickes , Steven J. Wittenberger , Lakshmi Bhagavatula , Thomas B. Borchardt
- Applicant: AbbVie Inc.
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07F7/08 ; C07D207/16 ; C07D401/04 ; C07D213/803
Abstract:
A process for making (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile and salts thereof, and intermediates used in the process are disclosed.
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