发明申请
US20160194635A1 METHOD OF ENHANCING MIR-185 EXPRESSION TO REDUCE LOW DENSITY LIPOPROTEIN/CHOLESTEROL ACCUMULATION IN A CELL
审中-公开
增强MIR-185表达以减少细胞中低密度脂蛋白/胆固醇积累的方法
- 专利标题： METHOD OF ENHANCING MIR-185 EXPRESSION TO REDUCE LOW DENSITY LIPOPROTEIN/CHOLESTEROL ACCUMULATION IN A CELL
- 专利标题（中）： 增强MIR-185表达以减少细胞中低密度脂蛋白/胆固醇积累的方法
-
申请号： US15004104申请日： 2016-01-22
-
公开(公告)号： US20160194635A1公开(公告)日： 2016-07-07
- 发明人: Muhua Yang , Joseph T. Nickels , Weidong Liu , Christina Ann Pellicane
- 申请人： Muhua Yang , Joseph T. Nickels , Weidong Liu , Christina Ann Pellicane
- 申请人地址： US NJ Hamilton
- 专利权人： Medical Diagnostic Laboratories, LLC
- 当前专利权人： Medical Diagnostic Laboratories, LLC
- 当前专利权人地址： US NJ Hamilton
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; C12Q1/68
摘要：
The present invention provides a method of quantifying miR-185 as a potential biomarker in lipid disorder or cardiovascular diseases in human. The present invention also provides a method of modulating miR-185 in regulating LDL and cholesterol metabolism in cells. The present invention has therapeutic potential in the treatment of cholesterol/LDL related cardiovascular diseases in humans.
公开/授权文献
信息查询
IPC分类:
